久久亚洲国产成人影院-久久亚洲国产的中文-久久亚洲国产高清-久久亚洲国产精品-亚洲图片偷拍自拍-亚洲图色视频

Global EditionASIA 中文雙語Fran?ais
Lifestyle
Home / Lifestyle / People

A lifetime searching for cures to end the scourge of malaria

By David Blair and Pan Mengqi | China Daily | Updated: 2018-04-07 10:38
Share
Share - WeChat

Traditional methods of dealing with malaria focus on mosquitoes, either trying to eliminate them or stopping them from biting people by using indoor spraying or distributing insecticide-infused sleeping nets.

Li has been a pioneer in applying an alternative approach called mass drug administration, which aims to eliminate the malaria parasite directly from the human population. The idea is to give artemisinin to all (or, as much as possible) of the population at one time thus eliminating malaria within a target region. Since malaria is not carried by animals, eliminating it from humans can get rid of the disease. Artemisinin is usually administered in a compound with another anti-malaria drug, because malaria is unlikely to be resistant to both.

He first tried mass drug administration in South China's Hainan province. "From 1975 to 1980, I engaged in research on MDA in Hainan, as it is the hottest zone in China. We handed medicine to patients three times a year in order to control the morbidity. But the effect was not very good, because only 60 to 70 percent of the people took the treatment. A lot of the elderly and children did not know we were sending out medicine, so they would not line up for it. Plus, at that time, the side effects of the medicine were relatively strong."

Cambodia is the second place where Li and his team tested the mass administration of artemisin compound therapy. He found high rates of uncontrolled malaria in the Mekong region. "At that time, the traditional way to control malaria was by eradicating mosquitoes, but I thought the key was to eradicating the plasmodium that humans carried. In the hot areas, over half of the people carried the parasite, reaching 80 to 90 percent in some regions."

"In 2004, there was an epidemic outbreak of malaria in Cambodia, so they allowed me to do a test. At that time I tried a method of hiring one person with a high school education as 'head warder' in every village. He registered all households, found out how many people were infected, then took the medicine house-to-house," Li says. In three years, the malaria rate fell by 95 percent. However, people brought in malaria from outside the target area, so the rate of infection rose again.

In 2006, Li and his team began a mass drug administration program in the island country of Comoros in East Africa. Li worked on the program there until 2008, when he had to return to China after having a stroke.

In a test case on the small Comoran island of Moheli, the cases of malaria fell by 94 percent within two months. Li also found that the malaria parasite had been greatly reduced both in humans and in mosquitoes: "The humans that carried the malaria parasite fell from 23 percent to 1 or 2 percent, and the portion of mosquitos carrying the parasite fell from 3 percent to nearly zero," Li says.

After applying mass drug administration of an artemisinin combination therapy to the Comoros' two other major islands, malaria cases fell from 103,000 around one-eighth of the population in 2010 to fewer than 2,000 cases in 2014. Deaths fell from 54 to zero, according to data from the Comoros Ministry of Health.

However, Li says his task is not finished. Without further work, malaria could come back. "Studies in Cambodia and the Comoros show that (mass drug administration) is the only way to control malaria quickly, but it failed to eliminate malaria," Li says.

"The first important point I proved in the Comoros was that the number of plasmodium-carried mosquitoes reduced as the number of human plasmodium-carriers decreased. The second point is, even after the MDA, there are still five to eight malaria patients every month. Though the number is small, there is a risk that the malaria could come back," Li says.

So Li continues his lifelong work. He and the team at Guangzhou University of Chinese Medicine are now working on a method, called PCR (polymerase chain reaction), that they have shown can effectively test for malaria using only one drop of blood.

"The cost of using PCR was $10 per person, which was too expensive for the local people. My team started to research our own reagent and succeeded. We reduced the cost from $10 to $1 a person, which makes PCR a popular, safe, fast and cheap way to check for malaria and ensure it does not come back" after mass drug administration, Li says.

|<< Previous 1 2   
Most Popular
Top
BACK TO THE TOP
English
Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
 
主站蜘蛛池模板: 日本韩国一区 | 国产系列在线播放 | 国产精品极品美女自在线看免费一区二区 | 亚洲天堂毛片 | 日本乱人伦片中文三区 | 韩国一级永久免费观看网址 | 久久久精品免费热线观看 | 日本一级特黄在线播放 | 中国欧美一级毛片免费 | 欧美极度另类 | 午夜黄色福利视频 | 欧美一级黄 | 欧美笫一页 | 一区不卡在线观看 | 女人张开双腿让男人桶完整 | 一级做a爱片久久毛片 | 亚洲精品久久久午夜伊人 | 国产成人精品免费视频大全办公室 | 免费a级毛片大学生免费观看 | 波多野结衣免费免费视频一区 | 欧美日韩高清在线观看一区二区 | 一级欧美一级日韩片 | 亚洲欧美日韩中文字幕在线一 | 成年女人看片免费视频频 | 欧美高清视频在线 | 2020久久国产最新免费观看 | 亚洲精品一区专区 | 精品视频亚洲 | 性欧美在线| 免费a级黄毛片 | 亚洲精品一区二区三区www | 国产一区二区三区久久小说 | 中国一级性生活片 | 国产一级黄毛片 | 日本一级特黄a大片在线 | 日本www在线播放 | 欧美成人高清视频 | 欧美精品亚洲精品日韩 | 99视频国产精品 | 成人在线精品 | 亚洲炮网 |